Watch the short lane with your life. EMP Kobolts are still not a problem, because they will be burned by Flame Auras. Skyguards and walls must be upgraded and/or repaired depending on lane activity. Prepare to lose your short lane wall from time to time – stunlock bosses as necessary. The left lanes and the back laneshould be mostly AFK. Watch out for hex throwers at wave 4. Weapon Man can be replaced by more auras, although with high gambit and Deadly Strikes, positioning may be tricky.

My ascension build on my first completed solo attempt is shown below. Only the relevant ascension points shown for brevity. All shards are maxed.
Ascension Recommended: 250 (84/83/83)

Monk (86/86/85)
Defense. Full Defense Speed, 60 Flame Aura Power, 6 LSA Power.
Utility. Full Defense Crit Chance, 25 FA Gambit.

• Flame Aura: 15.2k Mark
  • Deadly Strikes
  • Destruction
  • Defensive Critical Damage
• Lightning Strikes Aura: 14.6k Mark
  • Defense Rate
  • Destruction
  • Defensive Critical Damage
• Sky Guard Tower: 15k Totem
  • Vampiric Empowerment
  • Fortification
  • Deadly Strikes

Mystic (86/86/85)
Defense. Full Viper’s Fang Health.

• Viper’s Fangs (Wall): 15.5k Totem
  • Fortification
  • Power Pylon (or Explosive Guard)
  • Shielding Guard

Series EV2 (0/86/85)
Defense. 16 Weapon Manufacturer Damage.
Utility. Full Defense Crit Chance, 50 Defense Crit Damage.

• Weapon Manufacturer: 13.5k Mark
  • Defensive Critical Damage
  • Node Increase
  • Defensive Critical Strike